Role in Osteoporosis
نویسنده
چکیده
344 IntroductIon Calcium (Ca) is the most abundant inorganic element in human body along with sodium. Unique characteristic of calcium distribution in vivo with astronomical concentration gradients among the skeletal, extracellular and intracellular compartments ; 100,000,000 in bone, 10,000 in blood and 1 in intracellular compartment, provides the basis for its vital role in signal transduction and cellular function. Compromise of such concentration gradients on account of Ca deficiency and secondary hyperparathyroidism leading to bone Ca loss or osteoporosis and rise of intracellular free Ca ( [Ca]i) may lead to diseases of Ca paradox such as hypertension, arteriosclerosis, Alzheimer’s disease and other neurodegenerative diseases, osteoarthritis, diabetes mellitus and malignancy.
منابع مشابه
Performance of female teachers employed in education center in Rasht city regarding prevention of osteoporosis and their attitude on the role of mass media
Introduction: Osteoporosis is a silent disease that can cause decreased bone mass and put it at ‎risk of fracture. Therefore prevention at younger age can prevent its consequences.‎ Objective: The aim of this study was to determine the performance of female teachers about ‎osteoporosis and their attitude toward the role of media in its prevention.‎ Methods: In this descrip...
متن کاملP-181: Protective Role of Vitamin E As An Alternative Treatment for Ovariectomized Osteoporotic Rats
Background: Osteoporosis one of the postmenopausal symptoms is characterized by bone loss. There is a link between excessive reactive oxygen species (ROS) formation, estrogen deficiency due to cessation of ovarian function and bone loss. Free radicals are responsible for causing osteoblast apoptosis and reducing osteoblastogenesis in bone remodeling. Vitamin E is a potent antioxidant with the a...
متن کاملComparison of three different osteoporosis risk assessment tools: ORAI (osteoporosis risk assessment instrument), SCORE (simple calculated osteoporosis risk estimation) and OST (osteoporosis self-assessment tool)
Background :SCORE, OST and ORAI risk assessment tools could reduce the cost burden of BMD tests by selecting the high risk patients to osteoporosis. In this study we compared the ability of these risk assessment measures to assess probability of the osteoporosis among post-menopausal women. Methods : 211 post-menopausal women aged 45-88 years enrolled into the study. All of the patients und...
متن کاملبررسی شیوع استئوپروز و عدم همخوانی T-score ستون فقرات و فمور و برخی عوامل موثر در ایران: مطالعه آیموس
Background: Osteoporosis is the most prevalent metabolic bone disease which is characterized by low bone mass and increased risk of fracture. The present study was conducted to assess the prevalence of osteoporosis and T-score discordance between femur and lumbar spine as well as their risk factors in a group of healthy postmenopausal women and men older than 50 years old based on Iranian Multi...
متن کاملP-236: The Role of Trace Elements in Treatment of Ovariectomized Osteoporotic Rats
Background: Osteoporosis is one of the uncomfortable postmenopausal symptoms. The risk of imbalanced nutrition especially traces elements and vitamins are high during post menopause and may lead to osteoporosis due to reduction of content of mineral bone. The aim of this study was to investigate the potential consequence of Selenium (Se) treatment in ovariectomized rat model with osteoporosis i...
متن کاملKnowledge level of nurses employed in orthopedic units on osteoporosis disease
Introduction : Osteoporosis is a common problem of musculoskeletal system. Awareness of people about the etiology and risk factors could play an important role in taking care of themselves and others for prevention of osteoporosis. Objective : This study was performed to determine Knowledge level of nurses employed in orthopedic units on osteoporosis disease Materials...
متن کامل